Cipo 200 mg 20 capsules

Product Description:

Celecoxib 200 mg Capsules

What is Celecoxib and what is it used for?

• Celecoxib is used in adults to relieve the signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

• Celecoxib belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs).

• You should expect your medication to start working within hours of taking your first dose, but you may not feel the full effect for several days.

What you need to know before you take celecoxib:

Do not use celecoxib if:

• You are allergic to celecoxib or any of the other ingredients of this medicine.

• You have had an allergic reaction to a group of medicines called 'sulfonamides' (for example, some antibiotics used to treat infections)

• You currently have an ulcer in your stomach or intestine or bleeding in your stomach or intestine

• As a result of taking acetylsalicylic acid or any other nonsteroidal anti-inflammatory and pain-relieving medicine (NSAID) you have had asthma, nasal polyps, severe nasal congestion, or an allergic reaction such as a rash, itching, swelling of the face, lips, tongue, or throat, difficulty breathing, or wheezing

• You have severe liver disease.

• You have severe kidney disease.

• You have an inflammatory bowel disease such as ulcerative colitis or Crohn's disease.

• You have heart failure, established ischaemic heart disease, or cerebrovascular disease, for example. You have been diagnosed with a heart attack, stroke, transient ischaemic attack (a temporary reduction in blood flow to the brain; also known as a 'mini-stroke'), angina, or a blockage of a blood vessel to the heart or brain

• You have or have had blood circulation problems (peripheral arterial disease) or if you have had surgery on the arteries in your legs

Warnings and Precautions:

Talk to your doctor or pharmacist before taking celecoxib:

• If you have ever had an ulcer or bleeding in your stomach or intestines.

• If you are taking Celebrex at the same time as other NSAIDs that do not contain acetylsalicylic acid such as ibuprofen or diclofenac. You should avoid using these medicines together.

• If you are a smoker, have diabetes, high blood pressure or high cholesterol.

• If your heart, liver, or kidneys are not working well, your doctor may want to monitor your condition regularly.

• If you have fluid retention (such as swelling of the ankles and feet)

• If you are dehydrated, for example due to illness, diarrhoea or use of diuretics (used to treat excess fluid in the body)

• If you feel ill with an infection or think you have an infection, if you are over 65 years of age, your doctor will want to monitor you regularly

• Taking alcohol and NSAIDs may increase the risk of gastrointestinal problems.

Other medications and celecoxib

Celecoxib may interact with:

• Dextromethorphan (used to treat cough)

• Steroids (cortisone)

• ACE inhibitors, angiotensin II antagonists, beta blockers, and diuretics (used for high blood pressure and heart failure)

• Fluconazole and rifampicin (used to treat fungal and bacterial infections)

• Warfarin or other warfarin-like medicines (“blood thinning” agents that reduce blood clotting) including newer medicines such as apixaban

• Lithium (used to treat some types of depression).

• Other medications to treat depression, sleep disorders, high blood pressure, or irregular heartbeat

• Antipsychotics (used to treat some mental disorders)

• Methotrexate (used to treat rheumatoid arthritis, psoriasis, and leukemia)

• Carbamazepine (used to treat epilepsy/seizures and some forms of pain or depression)

• Barbiturates (used to treat epilepsy/seizures and some sleep disorders)

• Cyclosporin and tacrolimus (used to suppress the immune system, for example after a transplant)

• Celecoxib can be taken with a low dose of acetylsalicylic acid (75 mg or less daily). Ask your doctor for advice before taking both medicines together.

How to take celecoxib:

Celecoxib is for oral use. The capsules can be taken at any time of the day with or without food. However, try to take each dose of Celebrex at the same time each day.

Contact your doctor within two weeks of starting treatment if you do not experience any benefit.

The recommended dosage is:

One capsule daily, and your doctor may increase it to a maximum of two capsules, if necessary.

• Make sure your doctor knows if you have liver or kidney problems as you may need a lower dose.

Celecoxib is for adults only and not for children.

Possible side effects:

Stop using the product and seek immediate medical attention if you experience hives, rash, chest tightness, wheezing, chest pain, severe stomach pain, or jaundice.

How to store celecoxib:

• Keep this medicine out of the sight and reach of children.

• Do not use this medicine after the expiry date which is stated on the blister and carton. The expiry date refers to the last day of that month.

• Celecoxib should not be stored above 30°C.