Co-aprovel 150/12.5 mg 28 tablets

A valid prescription must be presented when receiving the application.

Irbesartan/Hydrochlorothiazide 150/12.5 mg

What is Irbesartan/Hydrochlorothiazide and what is it used for?

• It is a combination of irbesartan, an angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic, prescribed for high blood pressure:
• In patients who are not adequately controlled by monotherapy.
• As a first-line treatment for patients who are likely to require multiple medications to achieve their blood pressure goal.

Do not take irbesartan/hydrochlorothiazide :

• Allergy to irbesartan or hydrochlorothiazide
• Hypersensitivity to sulfonamide-derived drugs (such as sulfamethoxazole/trimethoprim, sulfasalazine)
• Anuria (not enough urine).
• kidney failure
• Liver failure

Warnings and Precautions:

• Talk to your doctor or pharmacist before taking irbesartan/hydrochlorothiazide:
• To monitor kidney function
• To monitor potassium levels
• If you have vision problems such as nearsightedness or glaucoma
• If you have lupus
• If you are at risk of dehydration

Possible side effects:

• fatigue
• dizziness
• muscle pain

Other medicines and irbesartan/hydrochlorothiazide:

• Tell your doctor or pharmacist about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
• Increased risk of lithium toxicity when taken together
• Increased risk of kidney damage and decreased effects when taken with nonsteroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors (such as ibuprofen, ketoprofen, celecoxib)
• It is not recommended to use it with potassium supplements to avoid high blood potassium levels.

With hydrochlorothiazide only:

• Avoid cholestyramine and colestipol for maximum absorption.
• Adjusting the dose of antidiabetic medications
• Monitor during use of alcohol, barbiturates, and narcotics due to possible hypotension.

How to take Irbesartan/Hydrochlorothiazide:

• Adults over 18 years of age with CrCl >30ml/min The usual dose is one tablet daily.
• Irbesartan/hydrochlorothiazide tablet can be taken with or without food.
• It can be taken at any time of the day.
• It can be given with other antihypertensive agents.
• Do not break the tablet in half.
• Correct if the amount of depletion is known before starting the medication.

How to store Irbesartan/Hydrochlorothiazide:

• Keep this medicine out of the sight and reach of children.
• Store at room temperature [77°F (25°C)].
• Do not store above 30 degrees.