Coveram 10 mg / 10 mg tablets

Koviram 10/10 mg tablets Active substance Perindopril 10 mg / Amlodipine 10 mg tablets Koviram tablets for treating high blood pressure and stable coronary artery disease, as the medication contains two active substances, which are perindopril and amlodipine. Perindopril is from the group of angiotensin-converting enzyme inhibitors, and amlodipine is from calcium channel blockers. They work to dilate blood vessels, thus blood flows easily. How Perindopril and Amlodipine Tablets Work Perindopril belongs to the "ACE inhibitors" group, a class of drugs primarily used to treat high blood pressure and heart failure. They work by causing relaxation and dilation of blood vessels as well as reducing blood volume, leading to lower blood pressure and decreased oxygen consumption by the heart. Additionally, perindopril prevents the conversion of angiotensin I to angiotensin II and prevents the breakdown of vasodilating prostaglandins, which reduces vasoconstriction regulated by angiotensin II and promotes vasodilation. Amlodipine prevents the flow of calcium ions into cells, with a greater effect on smooth muscle cells in blood vessels, leading to vasodilation and reduced vascular resistance to blood flow, thus lowering blood pressure. Medical Uses of Koviram Tablets Used to treat high blood pressure High blood pressure is a common condition where the long-term force of blood against the artery walls is high enough to eventually cause health problems, such as heart diseases. Lowering blood pressure reduces the risk of deadly and non-deadly cardiovascular diseases, especially stroke and myocardial infarction. How to Use Koviram Tablets Always take this medication exactly as your doctor told you. Consult your doctor or pharmacist if you are unsure. The tablets should be swallowed whole with a glass of water. Try to take your daily dose at about the same time each day. Continue taking the medication until your doctor tells you otherwise. The tablet should not be broken into halves. You can take the tablets with or without food. For treating high blood pressure: the usual dose is one tablet once daily, but your doctor may increase the dose to reach the target blood pressure. This medication is not recommended for use in children. The recommended starting dose is 2.5 mg of perindopril and 2.5 mg of amlodipine. The active substances are taken as separate tablets in elderly patients. This medication is indicated for long-term treatment. Doses may be changed in special circumstances, so always follow your doctor’s or pharmacist’s instructions. If you take more than you should, talk to your doctor or go to the hospital immediately. If you forget to take a dose, take it as soon as you remember unless it is time for the next dose. Do not take a double dose (two doses at the same time) to make up for the missed dose. Side Effects of Koviram Tablets Dizziness, headache, vertigo. Problems with vision. Tingling sensation like pins and needles. Tinnitus (ringing in your ears). Cough (dry and irritating). Swelling of ankles, feet, hands, or joints. Swelling and fluid retention. Chest pain and difficulty breathing. Dry mouth. Nosebleeds. Male sexual dysfunction. Changes in heart rate or rhythm (fast or irregular). Nausea, diarrhea, constipation, indigestion, taste changes, vomiting, abdominal pain. Low blood pressure, vasculitis, redness. Allergic reactions (such as eczema, itching, rash). Fatigue and tiredness. Drowsiness. Muscle cramps. Using Koviram Tablets During Pregnancy and Breastfeeding If you are pregnant or breastfeeding, think you might be pregnant, or plan to have a baby, ask your doctor or pharmacist for advice before taking this medication.