Zocor 40 mg tablet

Zocor 40 mg tablets Active ingredient Simvastatin What are the uses of Zocor? Used with dietary therapy to treat the following: Secondary prevention of the risk of cardiovascular diseases in patients with hypercholesterolemia with coronary heart disease or at risk of coronary artery diseases: reducing rates of heart diseases (myocardial infarction and coronary / non-coronary revascularization procedures) and deaths; and reducing the risk of stroke. Hyperlipidemia: to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, apolipoprotein B, triglycerides, very low-density lipoprotein (VLDL), and increasing high-density lipoprotein in patients with primary hypercholesterolemia. Familial hypercholesterolemia. What are the contraindications of Zocor? Active liver disease. Unexplained elevation of liver function tests (elevated aminotransferase enzymes). Breastfeeding. Pregnancy. Hypersensitivity to any component of the medication. What are the side effects of Zocor? Most common side effects: headache; mild muscle pain; joint pain; back pain; mild nausea; stomach pain or indigestion; constipation; or sleep problems (insomnia). What are the precautions for using Zocor? A cholesterol-lowering diet should be continued during treatment with this medication. It is advisable to avoid drinking large amounts of alcohol while taking this medication. Avoid drinking grapefruit juice while taking this medication, because grapefruit juice can affect simvastatin metabolism and increase the amount of medication in the blood, increasing the risk of side effects. This medication may rarely cause liver problems; therefore, your doctor will require blood tests to monitor liver function before starting treatment and regularly throughout. In very rare cases, this medication may cause muscle side effects; thus, you should inform your doctor immediately if you experience symptoms such as muscle pain, cramps, or weakness while taking this medication. This medication is not recommended for children under ten years of age. Used with caution in the following cases: Patients over 70 years old. Reduced kidney function. Reduced liver function. History of liver diseases. Patients who consume large amounts of alcohol. Thyroid diseases. History of hereditary muscle disorders. Hereditary blood disorders (porphyrias). History of muscle side effects during previous treatment with statins or fibrates. Pregnancy: should not be given to pregnant women or those planning pregnancy or suspecting pregnancy, as it may harm the fetus. Breastfeeding: it is unknown if it is excreted in breast milk; it is preferable to avoid it. What are the drug interactions of Zocor? If you are taking any of the following medications, inform your doctor or pharmacist, as you may need to adjust the dose or undergo certain tests: Amiodarone, amlodipine, azole antifungals (such as itraconazole, ketoconazole, posaconazole, voriconazole), colchicine, cyclosporine, danazol, daptomycin, delavirdine, diltiazem, dronedarone, pravastatin (e.g., gemfibrozil, clofibrate, fenofibrate), fosfomycin, boceprevir, telaprevir, ritonavir, ethinib, macrolide antibiotics (such as clarithromycin, erythromycin), mefibavirdil, nefazodone, niacin, ranolazine, risperidone, dalfopristin, quinupristin, telithromycin, or verapamil, as they may increase the risk of muscle or kidney problems. Bupropion, carbamazepine, efavirenz, rifampin, St. John’s Wort. Anticoagulants (such as warfarin), digoxin, tacrolimus. What are the dosage forms of Zocor? Tablets of 10 mg, 20 mg, 40 mg. What are the storage conditions for Zocor? Store at temperatures between 5 - 30 degrees Celsius, away from moisture and out of reach of children.