Sortiva - H - 100/12.5 tablets

Surtiva - H 100/12.5 tablets Active substance: Losartan potassium and Hydrochlorothiazide Coated tablets 100 mg / 25 mg What is Losartan potassium and Hydrochlorothiazide and what are its indications? Losartan is one of the angiotensin II receptor antagonists, and Hydrochlorothiazide is a diuretic. Angiotensin II is a substance produced by the body that binds to receptors in blood vessels, causing them to constrict. This medication is prescribed for the treatment of primary hypertension (high blood pressure). Do not take Losartan potassium and Hydrochlorothiazide: • If you are allergic to Losartan or Hydrochlorothiazide or any other ingredients of this medication, • If you are allergic to other sulfonamide derivatives, • If you have severe liver impairment, • If you have low levels of potassium or sodium or high calcium levels that cannot be corrected by treatment, • If you are pregnant for more than 3 months, • If you have severe kidney impairment or if the kidneys are not producing any urine, • If you have diabetes or kidney dysfunction and are being treated with a blood pressure-lowering medication containing Spironolactone. Precautions and warnings: Talk to your doctor or pharmacist before taking this medication: • If you have previously experienced swelling of the face, lips, throat, or tongue, • If you are taking diuretics (water pills), • If you follow a low-salt diet, • If you have or have had severe vomiting and/or diarrhea, • If you have heart failure, • If you have liver impairment, • If you have narrowing of the arteries in your kidneys or if you have only one kidney, or if you recently had a kidney transplant, • If you have arterial narrowing, angina, • If you have "aortic stenosis or mitral valve stenosis" or "hypertrophic cardiomyopathy", • If you have diabetes, • If you have had gout, • If you have or have had allergy or asthma or a condition causing joint pain, skin rash, or fever, • If you have high calcium or low potassium levels or are following a low-potassium diet. Possible side effects of Losartan potassium and Hydrochlorothiazide: Common side effects: • Cough, upper respiratory infection, nasal congestion, sinusitis, sinus discomfort, • Diarrhea, abdominal pain, nausea, indigestion, • Muscle pain or cramps, leg pain, back pain, • Insomnia, headache, dizziness, • Weakness, fatigue, chest pain, • Increased potassium levels and decreased hemoglobin levels, • Changes in kidney function including renal failure, • Severe hypoglycemia (low blood sugar). Other medications and Losartan potassium and Hydrochlorothiazide: Many drugs can interact with this medication, potentially altering their effects significantly. These include: • Potassium supplements or salt substitutes containing potassium, or medications that retain potassium or may increase blood potassium levels, • Other blood pressure-lowering drugs, • Stimulants, • Cancer treatments, • Pain relievers, • Antifungal medications, • Arthritis medications, • Cholesterol-lowering resins like Cholestyramine, • Muscle relaxants, • Sleep aids, • Opioids like Morphine, • Oral diabetes medications or Insulin. How to take Losartan potassium and Hydrochlorothiazide: The usual dose for most patients with hypertension is one tablet of Losartan potassium and Hydrochlorothiazide 50 mg / 12.5 mg daily to control blood pressure over 24 hours. It can be increased to two tablets once daily of Losartan / Hydrochlorothiazide 50 mg / 12.5 mg. The maximum daily dose is 2 tablets of Losartan / Hydrochlorothiazide 50 mg / 12.5 mg coated tablets. • Tablets should be swallowed whole with a glass of water. How to store Losartan potassium and Hydrochlorothiazide: Keep this medication out of sight and reach of children. • Do not use this medication after the expiration date printed on the packaging. The expiration date refers to the last day of that month. • Store this medication in the original container to protect it from light and moisture. The container should not be stored above 30°C.