Daonil tablets 2.5 / 500 mg

Duanil M 2.5/500 tablets Active ingredient Glibenclamide + Metformin hydrochloride Lower blood sugar level Used combination of Glibenclamide / Metformin hydrochloride to lower blood sugar levels in type 2 diabetes (not insulin-dependent) as an addition to a healthy diet and exercise. Do not take Glibenclamide / Metformin hydrochloride: • If you have an allergy to Glibenclamide, Metformin, other sulfonylureas, sulfonamides, or any other ingredients of this medicine. • If you suffer from type 1 diabetes (insulin-dependent). • If you have diabetic ketoacidosis (serious complication where blood sugar levels are very high and you experience nausea, frequent urination, fatigue, muscle weakness). • If you have severe liver problems. • If you have kidney problems. • If you are dehydrated (lost a lot of water from your body due to prolonged or severe diarrhea, or if you have vomited several times in a row). • If you have a severe infection, such as lung or kidney infection. • If you have acute heart failure or recently had a heart attack, or have serious vascular problems or breathing difficulties. • If you are taking a medication called Pusentan for high blood pressure. • If you consume excessive alcohol. Precautions: Tell your doctor about all your health conditions, including if you have: • If you are recovering from an injury, surgery, fever infection, or other forms of stress. • If you have liver or kidney problems. • If you have a deficiency of an enzyme called Glucose-6-Phosphate Dehydrogenase (G6PD). • If you have a heart disease. • You should stop taking this medication for a period before major surgery. Talk to your doctor. • This medication may cause a rare but serious complication called lactic acidosis. Signs include abdominal pain, vomiting, muscle cramps, extreme fatigue, difficulty breathing, low body temperature, and rapid heartbeat. • This medication may cause a decrease in blood sugar levels, especially if you miss a meal, exercise excessively, or drink alcohol. Signs of low blood sugar include nausea, hunger, shivering, dizziness, confusion, drowsiness, difficulty speaking, sweating. You can eat a sugar cube or some juice. Possible side effects: Stop using this product and seek immediate medical care if you develop a rash; itching; red, ulcerated, or peeling skin; chest or throat tightness; difficulty breathing, swallowing, or speaking; unusual hoarseness; swelling of the mouth, face, lips, tongue, or throat. The frequency of these side effects is unknown. Serious side effects: • Allergic reactions • Low blood sugar • Liver problems • Lactic acidosis Other medications and Glibenclamide / Metformin hydrochloride: Tell your doctor about all medications you are taking. Glibenclamide / Metformin hydrochloride interacts with many drugs including: • Other diabetes medications • Some blood pressure medications • Birth control pills • Medications for mood disorders • Some antibiotics • Steroid-free anti-inflammatory drugs • Corticosteroids • Anticoagulants like Warfarin • Phenytoin • Digoxin • Some cholesterol-lowering drugs • Some asthma medications like Salbutamol • Imaging dyes used in radiology How to take Glibenclamide / Metformin hydrochloride: • This medication is for adults only. • Take this medication as prescribed by your doctor. • Take this medication with food. • The usual starting dose is Glibenclamide 1.25 - 2.5 mg / Metformin 500 - 1000 mg. Given once or twice daily. Storage instructions for Glibenclamide / Metformin hydrochloride: • Store at room temperature between 68 to 77 degrees Fahrenheit (20 to 25 degrees Celsius). • Keep this medicine out of reach of children. • Do not use this medicine after the expiration date printed on the package.