Janumet XR 50/1000 mg 56 tablets

Janumet® XR extended-release tablets 50 mg / 500 mg, 50 mg / 1000 mg, and 100 mg / 1000 mg sitagliptin and metformin hydrochloride this medicine was prescribed for you. Do not give it to others. It may harm them, even if their symptoms are similar to yours. What is Janumet XR and its indications: Janumet XR is a tablet containing two prescription drugs, sitagliptin phosphate and metformin. Sitagliptin, a member of a class of drugs called DPP-4 inhibitors, and metformin, a member of the biguanide class of drugs, work together to control blood sugar levels in patients with type 2 diabetes mellitus, also called non-insulin-dependent diabetes mellitus or NIDD. Your doctor prescribed Janumet XR to help lower blood sugar levels, which are very high due to type 2 diabetes and cannot be controlled through diet and exercise alone. Janumet XR helps improve post-meal insulin levels and reduce the amount of sugar the body produces. Janumet XR helps the body respond better to naturally produced insulin. Janumet XR should only be taken with a doctor's prescription. When should I not use Janumet XR: Do not take Janumet XR if you are allergic to the active ingredient or any inactive ingredient. You have type 1 diabetes, or conditions called diabetic ketoacidosis or diabetic metabolic acidosis (increased ketones in blood or urine), or if you have serious kidney problems. Do not take Janumet XR also if you have: conditions that can lead to kidney problems such as some heart diseases and certain types of serious infections like high fever, diarrhea, and/or vomiting (significant fluid loss). Undergo or receive an injection of contrast dye or contrast agent for X-ray procedures. Talk to your doctor about when to stop Janumet XR and when to start again. When should I be cautious when taking Janumet XR: Tell your doctor if you have: kidney problems, liver problems, heart problems including congestive heart failure (when the heart does not pump blood sufficiently), heavy alcohol consumption (all the time or binge drinking for a short period), pregnancy or planning pregnancy, breastfeeding, or a condition that may be associated with dehydration (severe fluid loss) such as severe vomiting, diarrhea, or fever, or if you drink much less fluids than usual. If you need surgery while taking Janumet XR: Cases of pancreatitis (inflammation of the pancreas) have been reported in patients taking Janumet XR. Pancreatitis can be a serious life-threatening condition. Stop taking Janumet XR and contact your doctor if you experience severe and persistent stomach pain, with or without vomiting, as it may be pancreatitis. Consult your doctor immediately if you experience: unexplained muscle pain or tenderness or weakness, as muscle problems can be serious, including muscle breakdown that can lead to kidney damage. Cases of a skin reaction called bullous pemphigoid have been reported in patients taking Janumet XR. See your doctor if you develop blisters or skin erosion (erosion). This medical product contains less than 1 millimole of sodium (23 mg) per tablet, essentially "sodium-free." Use in children and adolescents: Janumet XR has not been studied in children and adolescents under 18 years old and should not be used in them. Use in the elderly: Janumet XR should only be used in elderly patients under regular medical supervision. Tell your doctor or pharmacist if you have other illnesses or allergies or are taking other medications (including over-the-counter drugs!). Can I take Janumet XR during pregnancy or breastfeeding? Pregnant women or those planning pregnancy should consult a doctor before not using Janumet XR. Janumet XR during pregnancy. It is unknown whether Janumet XR passes into breast milk. Do not use Janumet XR if you are breastfeeding or planning to breastfeed. Talk to your doctor. How to take Janumet XR: Take Janumet XR exactly as prescribed by your doctor, who will tell you how many Janumet XR tablets to take. Your doctor may need to increase your dose to control blood sugar. Your doctor may prescribe Janumet XR with a sulfonylurea or insulin (other blood sugar-lowering medications). Take Janumet XR once daily with the evening meal to reduce the likelihood of stomach upset. If you are taking Janumet XR, swallow the tablets whole—do not chew, break, or crush the tablets. Tell your doctor if you cannot swallow Janumet XR whole. You may see something that looks like a Janumet XR tablet in your stool if you see several tablets in your bowel movement. Sometimes, talk to your doctor. Do not stop taking Janumet XR without talking to your doctor. Continue taking Janumet XR as long as your doctor has prescribed so you can keep helping control blood sugar levels. You may need to stop Janumet XR for a short period; contact your doctor for instructions if you: have a condition that may be associated with dehydration (severe fluid loss) such as severe vomiting, diarrhea, or fever, or if you drink much less fluids than usual; plan to undergo surgery; will receive or are receiving an injection of contrast dye or contrast agent for X-ray procedures. A healthy diet and exercise can help your body use blood sugar better, and it is important to follow your doctor’s recommended diet, exercise, and weight loss program while taking Janumet XR. If you take more than the prescribed dose of Janumet XR, contact your doctor immediately. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not take a double dose of Janumet XR. If you have taken more than prescribed, talk to your doctor or pharmacist. If you feel the medication is not effective or too strong, discuss this with your doctor or pharmacist. Possible side effects: In rare cases, metformin, one of the drugs in Janumet XR, can cause serious side effects called lactic acidosis. Lactic acidosis is a medical emergency that can cause death and requires hospital treatment. It involves lactic acid in your blood. Stop taking Janumet XR if you experience symptoms of lactic acidosis: feeling very weak and tired, unusual muscle pain, difficulty breathing, stomach pain with nausea and vomiting or diarrhea, feeling cold especially in your arms and legs, dizziness or lightheadedness, slow or irregular heartbeat, sudden change in your medical condition. You are at higher risk of lactic acidosis if you: have severe kidney problems, liver problems, congestive heart failure requiring medication, drink a lot of alcohol (frequently or binge drinking), are dehydrated (lose a large amount of body fluids), have had surgery, have a heart attack or severe infection or stroke. Other common side effects in patients taking Janumet XR include: headache, low blood sugar (hypoglycemia), gastrointestinal symptoms such as diarrhea, nausea, indigestion, bloating, vomiting, metallic taste, stomach pain, loss of appetite. Most of these side effects occur early in treatment and go away without stopping the medication. Blood cell counts and platelets may decrease. Nasal congestion, sore throat, upper respiratory infection, headache may also occur. Taking Janumet XR with meals may reduce stomach problems; however, if you experience unusual or unexpected stomach issues, talk to your doctor. Starting later during treatment may be a sign of something more serious. When using Janumet XR with a sulfonylurea or insulin, low blood sugar (hypoglycemia) can occur due to the sulfonylurea or insulin. Your doctor will reduce the dose of these medications. Additionally, when using Janumet XR with a sulfonylurea, constipation may occur. Additional side effects reported with Janumet XR or sitagliptin include allergic reactions that can be severe, such as rash, hives, swelling of the face, lips, tongue, or throat, which may cause breathing or swallowing difficulties. If you have an allergic reaction, stop taking Janumet XR and contact your doctor immediately. Your doctor may prescribe medication for your allergic reaction and a different medication for your diabetes. Pancreatitis: Stop taking Janumet XR and contact your doctor immediately if you experience severe and persistent stomach pain, with or without vomiting. Kidney problems (sometimes requiring dialysis). Joint pain. Muscle pain. Arm or leg pain. Back pain. Blisters on the skin. Contact your doctor immediately if you experience muscle pain, tenderness, or weakness, as muscle problems can be serious, including muscle fiber breakdown that can lead to kidney damage and death. This risk may be higher in older patients (65 years and older). Female gender, kidney disease, thyroid disease. Other side effects not listed above may occur in some patients: inform your doctor or pharmacist if you notice any side effects not described here. If you experience unusual symptoms or if any known symptoms persist or worsen. Reporting side effects: if you experience any side effects, talk to your doctor. This includes any potential side effects not listed in this leaflet. You can also report side effects directly through the National Pharmacovigilance Center (NPC), the Saudi Food and Drug Authority, by reporting side effects, you can help provide more information about the safety of this medicine. How to store Janumet XR: Keep out of reach and sight of children. Store at temperatures below 30°C. Do not use this medicine after the expiration date printed on the label after EXP. Do not dispose of medicines in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer needed. These procedures help protect the environment. Contents of the package and other information: What Janumet XR contains: Ingredients: Sitagliptin, such as sitagliptin phosphate monohydrate, metformin hydrochloride. Janumet XR 50 mg / 500 mg contains 50 mg sitagliptin, such as sitagliptin phosphate monohydrate, and 500 mg metformin as metformin hydrochloride. Janumet XR 50 mg / 1000 mg contains 50 mg sitagliptin, such as sitagliptin phosphate monohydrate, and 1000 mg metformin as metformin hydrochloride. Janumet XR 100 mg / 1000 mg contains 100 mg sitagliptin, such as sitagliptin phosphate monohydrate, and 1000 mg metformin as metformin hydrochloride. Packaging contents: Janumet XR 50 mg / 500 mg is available in bottles with 56 coated tablets. The 50 mg / 500 mg tablets are light blue, biconvex, oval film-coated tablets with "78" engraved on one side. Janumet XR 50 mg / 1000 mg is available in bottles with 56 coated tablets. The 50 mg / 1000 mg tablets are light green, biconvex, oval film-coated tablets with "80" engraved on one side. Janumet XR 100 mg / 1000 mg is available in bottles with 28 coated tablets. The 100 mg / 1000 mg tablets are blue, biconvex, oval film-coated tablets with "81" engraved on one side. Product details: Brand: Janumet. Product model: Tablets.