Xtandi 40 mg enzalutamide capsules × 112

What is Enzalutamide and its indications for use: Enzalutamide is used for treating adult men with prostate cancer who no longer respond to androgen deprivation therapy. How Enzalutamide works: Enzalutamide is a medicine that works by blocking the activity of hormones called androgens (such as testosterone). By blocking androgens, Enzalutamide stops prostate cancer cells from growing and dividing. What you need to know before using Enzalutamide: Do not use Enzalutamide: If you are allergic to Enzalutamide or any other ingredients in these tablets If you are pregnant or may become pregnant Precautions and warnings: Seizures: Seizures have been reported in 4 out of 1000 people taking Enzalutamide, and less than 1 out of 1000 people taking placebo If you are taking medication that can cause seizures or increase seizure risk If you have a seizure during treatment: see your doctor as soon as possible. Your doctor may decide that you should stop taking Enzalutamide. Reversible Posterior Leukoencephalopathy Syndrome (PRES): There have been rare reports of PRES, a rare reversible condition involving the brain, in patients treated with Enzalutamide. If you experience a seizure or worsening headache, confusion, blindness, or other vision problems, contact your doctor as soon as possible. Talk to your doctor before taking Enzalutamide: If you are taking any blood thinners (such as warfarin, acenocoumarol, clopidogrel) If you are using chemotherapy such as docetaxel If you have liver problems If you have kidney problems If you have any heart or vascular diseases, including arrhythmias, or are being treated with medications for these conditions. The risk of heart rhythm problems may increase when using Enzalutamide. Children and adolescents: This medicine is not intended for children and adolescents. Other medicines and Enzalutamide: Tell your doctor if you are taking any of the following: When taken together with Enzalutamide, these medicines may increase the risk of seizures: some medicines used to treat asthma and other respiratory diseases (such as aminophylline, theophylline). Medicines used to treat certain mental disorders such as depression and schizophrenia (such as clozapine, olanzapine, risperidone, ziprasidone, bupropion, lithium, chlorpromazine, mesoridazine, thioridazine, amitriptyline, desipramine, doxepin, imipramine, maprotiline). Certain pain medications (such as pethidine). Tell your doctor if you are taking the following medicines: These medicines may affect the effect of Enzalutamide, or Enzalutamide may affect the effect of these medicines. This includes some medicines used in: lowering cholesterol (such as gemfibrozil, atorvastatin, simvastatin) pain relief (such as fentanyl, tramadol) cancer treatment (such as cabazitaxel) epilepsy treatment (such as carbamazepine, clonazepam, phenytoin, primidone, valproic acid) treatment of certain mental disorders like severe anxiety or schizophrenia (such as diazepam, midazolam, haloperidol) sleep disorders (such as zolpidem) heart diseases or low blood pressure (such as bisoprolol, digoxin, diltiazem, felodipine, nicardipine, nifedipine, propranolol, verapamil) serious infectious diseases (such as dexamethasone, prednisone) HIV infection treatment (such as indinavir, ritonavir) bacterial infections treatment (such as clarithromycin, doxycycline) thyroid disorders treatment (such as levothyroxine) gout treatment (such as colchicine) stomach disorders treatment (such as omeprazole) prevention of heart diseases or strokes (such as dabigatran etexilate) organ rejection prevention (such as tacrolimus) Enzalutamide may interfere with some medicines used to treat heart rhythm problems (such as quinidine, procainamide, amiodarone, sotalol) or may increase the risk of heart rhythm issues when used with other medicines (such as methadone, used for pain relief and part of drug detoxification, moxifloxacin, an antibiotic, antipsychotics used for mental illnesses). How to use Enzalutamide: Always take this medicine exactly as your doctor has told you. Consult your doctor if you are unsure. The usual dose is 160 mg (four soft capsules) taken at the same time once daily. Swallow the soft capsules whole with water. Do not chew, dissolve, or open the soft capsules before swallowing. Enzalutamide can be taken with or without food. Enzalutamide should not be handled by anyone other than the patient and their caregivers, especially pregnant women or those who may become pregnant. Your doctor may also prescribe other medications while you are taking Enzalutamide. Possible side effects: Stop using the product and seek immediate medical care if: Swelling of the face, lips, tongue, or throat that may cause difficulty breathing or swallowing Common side effects: Headache Drowsiness Anxiety Dry skin and itching Memory difficulty Heart artery blockage (coronary artery disease) Enlarged breasts in men (gynecomastia) Restless legs syndrome symptoms (an uncontrollable urge to move a part of the body, usually the leg) Decreased concentration and forgetfulness Less common side effects: Hallucinations Difficulty thinking clearly Decreased white blood cell count Storage of Enzalutamide: Keep this medicine out of sight and reach of children. Do not use this medicine after the expiration date printed on the outer carton and blister pack after EXP. The expiration date refers to the last day of that month. This medicine does not require special storage conditions. Do not take any soft capsule that is leaking, damaged, or shows signs of tampering. Do not dispose of medicines in wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These procedures help protect the environment. Product details: Brand: Zatendin Product model: Capsules Product type: Capsules