Xtandi 40 mg enzalutamide capsules × 112

What is Enzalutamide and its indications: Enzalutamide is used for treating adult men with prostate cancer who no longer respond to androgen deprivation therapy. How Enzalutamide works: Enzalutamide is a medicine that works by blocking the activity of hormones called androgens (like testosterone). By blocking androgens, Enzalutamide stops prostate cancer cells from growing and dividing. What you need to know before using Enzalutamide: Do not use Enzalutamide: If you are allergic to Enzalutamide or any other ingredients in these tablets. If you are pregnant or may become pregnant. Precautions and warnings: Seizures: Seizures have been reported in 4 out of 1000 people taking Enzalutamide, and less than 1 out of 1000 people taking placebo. If you are taking a medicine that can cause seizures or increase seizure risk. If you have a seizure during treatment: see your doctor as soon as possible. Your doctor may decide that you should stop taking Enzalutamide. Reversible posterior leukoencephalopathy syndrome (PRES): Rare reports of PRES, a rare reversible condition involving the brain, have been documented in patients treated with Enzalutamide. If you experience a seizure or worsening headache, confusion, blindness, or other vision problems, contact your doctor immediately. Talk to your doctor before taking Enzalutamide: If you are taking any blood thinners (like warfarin, acenocoumarol, clopidogrel). If you are using chemotherapy such as docetaxel. If you have liver problems. If you have kidney problems. If you have any heart or vascular diseases, including arrhythmias, or are being treated with medications for these conditions. The risk of heart rhythm problems may increase when using Enzalutamide. Children and adolescents: This medicine is not intended for children and adolescents. Other medications and Enzalutamide: Inform your doctor if you are taking any of the following: When taken together with Enzalutamide, these medications may increase the risk of seizures: Some medicines used for asthma and respiratory diseases (like aminophylline, theophylline). Medicines used for certain mental disorders such as depression and schizophrenia (like clozapine, olanzapine, risperidone, ziprasidone, bupropion, lithium, chlorpromazine, mesoridazine, thioridazine, amitriptyline, desipramine, doxepin, imipramine, maprotiline). Certain pain medications (like pethidine). Tell your doctor if you are taking the following medicines: These drugs may affect the effect of Enzalutamide, or Enzalutamide may affect the effect of these drugs. This includes some medications used for: Lowering cholesterol (like gemfibrozil, atorvastatin, simvastatin). Pain relief (like fentanyl, tramadol). Cancer treatment (like cabazitaxel). Treating epilepsy (like carbamazepine, clonazepam, phenytoin, primidone, valproic acid). Treating certain mental disorders like severe anxiety or schizophrenia (like diazepam, midazolam, haloperidol). Treating sleep disorders (like zolpidem). Heart disease or low blood pressure (like bisoprolol, digoxin, diltiazem, felodipine, nicardipine, nifedipine, propranolol, verapamil). Serious infectious diseases (like dexamethasone, prednisone). HIV infection treatment (like indinavir, ritonavir). Bacterial infections treatment (like clarithromycin, doxycycline). Thyroid disorders treatment (like levothyroxine). Gout treatment (like colchicine). Stomach disorders treatment (like omeprazole). Preventing heart diseases or strokes (like dabigatran etexilate). Organ rejection prevention (like tacrolimus). Enzalutamide may interfere with some heart rhythm medications (like quinidine, procainamide, amiodarone, sotalol) or increase the risk of heart rhythm problems when used with other drugs (like methadone, used for pain relief and part of drug detoxification, moxifloxacin, an antibiotic, antipsychotics for mental illnesses). How to use Enzalutamide: Always take this medicine exactly as your doctor has told you. Consult your doctor if you are unsure. The usual dose is 160 mg (four soft capsules) taken at the same time once daily. Swallow the soft capsules whole with water. Do not chew, dissolve, or open the soft capsules before swallowing. Enzalutamide can be taken with or without food. Enzalutamide should not be handled by anyone other than the patient and their caregivers, especially pregnant women or women who may become pregnant. Your doctor may also prescribe other medicines while you are taking Enzalutamide. Possible side effects: Stop using the product and seek immediate medical attention if: Face, lips, tongue, or throat swelling that may cause difficulty breathing or swallowing. Common side effects: Headache, fall, feeling anxious, dry skin and itching, difficulty remembering, coronary artery blockage (ischemic heart disease), enlarged breasts in men (gynecomastia), symptoms of restless legs syndrome (an uncontrollable urge to move a part of the body, usually the legs), decreased concentration and forgetfulness. Uncommon side effects: Hallucinations, difficulty thinking clearly, low white blood cell count. How to store Enzalutamide: Keep this medicine out of sight and reach of children. Do not use this medicine after the expiration date printed on the outer carton and blister pack after EXP. The expiration date refers to the last day of that month. This medicine does not require special storage conditions. Do not take any soft capsule that is leaking, damaged, or shows signs of tampering. Do not dispose of medicines in wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These procedures help protect the environment. Product details: Product model: Capsules. Product type: Capsules. Brand: Zatandi.