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What Glimepiride is used for: Glimepiride is used to lower blood sugar levels in patients with type 2 diabetes mellitus, along with a healthy diet and exercise. Do not take Glimepiride: if you are allergic to Glimepiride or sulfonylureas or sulfonamides or any other component of this medicine. if you have type 1 diabetes mellitus (insulin-dependent). if you have diabetic ketoacidosis (an emergency condition where your blood sugar levels are very high and you experience nausea, frequent urination, fatigue, and muscle weakness). if you are in diabetic coma. if you have serious liver problems. if you have kidney problems. Precautions and warnings: Talk to your doctor about all your medical conditions before taking this medicine, including: if you are recovering from an injury or surgery or a fever infection or other forms of stress. if you have liver or kidney problems. if you have a deficiency of an enzyme called glucose-6-phosphate dehydrogenase (G6PD). This medicine may cause low blood sugar levels (hypoglycemia), especially if you miss a meal, exercise more, or drink alcohol. Symptoms include: nausea, hunger, shivering, dizziness, confusion, drowsiness, insomnia, difficulty speaking, sweating. You can take a sugar cube or some sweet juice to help. Possible side effects: Stop using this product and seek immediate medical help if you develop a rash; chills; itching; red or swollen or ulcerated or peeling skin; wheezing; chest or throat tightness; difficulty breathing or swallowing or speaking; unusual hoarseness or swelling of the mouth or face or lips or tongue or throat. Serious side effects: allergic reactions, low blood sugar levels (hypoglycemia), liver problems. Other medicines and Glimepiride: Tell your doctor about all the medicines you are taking. Glimepiride interacts with many medicines including: pain and inflammation medications, other diabetes medications, anticoagulants like warfarin, medications used to treat high blood pressure, medications used for arrhythmias, medications to lower cholesterol, medications for mood disorders, some antibiotics, antifungal medications, cancer treatments, oral contraceptives, asthma and nasal congestion medications, stimulants, medications for stomach ulcers. How to take Glimepiride: This medicine is for adults only. Take it as directed by your doctor. Take with food, with the first meal of the day. The usual starting dose is one 1 mg tablet once daily with breakfast. Your doctor may gradually increase it up to a maximum of 8 mg per day. How to store Glimepiride: Store at room temperature from 68 to 77 degrees Fahrenheit (20 to 25 degrees Celsius). Keep this medicine out of reach of children. Do not use this medicine after the expiration date printed on the packaging. The expiration date refers to the last day of the same month.