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Perindopril Arginine Tablets 10 mg What is Perindopril Arginine and what is its use: Perindopril Arginine is a medicine belonging to a class of drugs known as "ACE inhibitors". It works by dilating blood vessels, making it easier for your heart to pump blood through them. Perindopril Arginine is used for the following indications: to treat high blood pressure. to treat heart failure (a disorder that makes the heart muscle unable to pump blood properly). to reduce the risk of cardiac events, such as heart attacks, in patients with stable coronary artery disease (a disorder where blood flow to the heart is blocked or reduced) and in patients who have previously experienced a heart attack and/or procedures to improve blood flow to the heart by dilating blood vessels. Do not take Perindopril Arginine: if you are allergic to Perindopril or any other components of this medicine, or to any other ACE inhibitors. if you have previously experienced angioedema caused by Perindopril or another ACE inhibitor. Angioedema is a condition characterized by signs and symptoms such as swelling of the face, throat, or tongue, wheezing, severe itching, or severe rash. if a family member has previously experienced angioedema caused by Perindopril or another ACE inhibitor. if you are pregnant for more than 3 months. if you have diabetes or kidney problems and are taking Lisinopril. Warnings and precautions: stop taking the medicine immediately and talk to your doctor or pharmacist if you experience allergic reactions such as difficulty breathing, rash, swelling of the face or neck, low blood pressure, or dizziness. talk to your doctor if you have hypertrophic cardiomyopathy (a heart muscle problem), aortic stenosis (narrowing of the main blood vessels leading to the heart), or renal artery stenosis (narrowing of the artery supplying blood to the kidneys). talk to your doctor before starting this medicine if you have liver or kidney problems or if you are undergoing dialysis. talk to your doctor before starting this medicine if you have diabetes. talk to your doctor before starting this medicine if you have a connective tissue disorder such as scleroderma or systemic lupus erythematosus. talk to your doctor before starting this medicine if you follow a salt-restricted diet or use salt substitutes containing potassium. talk to your doctor before starting this medicine if you will undergo LDL apheresis (removal of cholesterol from your blood using a machine). talk to your doctor before starting this medicine if you will undergo surgery and/or anesthesia. talk to your doctor before starting this medicine if you will undergo allergy desensitization treatment to reduce the effects of wasp or bee stings. talk to your doctor before starting this medicine if you are intolerant to certain sugars. talk to your doctor before starting this medicine if you have recently experienced vomiting, diarrhea, or dehydration. talk to your doctor before starting this medicine if you are pregnant or planning pregnancy. Possible side effects: potential side effects include angioedema (swelling with a red skin rash under the skin in a localized part of the body on the hands, feet, lips, or around the eyes), dizziness, headache, vision problems, tingling sensations, ringing in the ears, cough, shortness of breath, nausea, diarrhea, constipation, indigestion, taste changes, vomiting, abdominal pain, allergic reactions (such as itching and rash), fatigue, and muscle cramps. Other medications and Perindopril Arginine: inform your doctor or pharmacist if you are currently taking, have recently taken, or might take any other medications, including over-the-counter drugs, prescribed medications, herbal supplements, vitamins, and supplements. if you are taking antihypertensive medications (such as Lisinopril). if you are taking diuretics (used to increase urination). if you are taking non-steroidal anti-inflammatory drugs (used to reduce inflammation, pain, and fever like Ibuprofen) or high doses of aspirin. if you are taking medications for diabetes (such as Metformin or Insulin). if you are taking Lithium (used for depression or mania). if you are taking Eplerenone (used to treat heart failure). if you are taking potassium-sparing medications (such as Spironolactone, Amiloride, Triamterene), potassium-containing salt substitutes, or potassium supplements. if you are taking Baclofen (used to treat muscle stiffness in conditions like multiple sclerosis). if you are taking immunosuppressants (used to reduce body defenses after transplantation or to treat autoimmune disorders like Cyclosporine and Tacrolimus). if you are taking medications for mental health disorders such as anxiety, depression, or schizophrenia (such as antipsychotics and tricyclic antidepressants). if you are taking Heparin (blood thinner). if you are taking Procainamide (used to treat arrhythmias). if you are taking Estramustine (used for cancer). if you are taking Allopurinol (used for gout). if you are taking gold salts, especially when administered intravenously (used to treat rheumatoid arthritis symptoms). if you are taking Trimethoprim (used for infections). if you are taking vasodilators including nitrates (medications to dilate blood vessels). if you are taking medications for asthma, shock, or low blood pressure (such as Ephedrine, Adrenaline, or Noradrenaline). How to take Perindopril Arginine: High blood pressure the recommended dose is 5 mg once daily. The dose can be increased to 10 mg once daily if needed after one month. The maximum dose is 10 mg daily. If you are 65 years or older, the initial recommended dose is 2.5 mg orally once daily. The dose can be increased to 5 mg once daily after one month, then to 10 mg once daily if needed. Heart failure the recommended dose is 2.5 mg orally once daily. The dose can be increased to 5 mg once daily after two weeks. The maximum recommended dose is 5 mg once daily. Stable angina the initial recommended dose is 5 mg once daily. The dose can be increased to 10 mg once daily after two weeks. The maximum recommended dose is 10 mg once daily. If you are 65 years or older, the initial recommended dose is 2.5 mg once daily. The dose can be increased to 5 mg once daily after one week, then to 10 mg once daily after another week. Children and adolescents are not advised to use this medicine. Take the tablet before breakfast in the morning. Take the tablet with a full glass of water. Take the medicine exactly as prescribed by your doctor. Consult your doctor or pharmacist if you are unsure. How to store Perindopril Arginine: keep the medicine out of reach of children and pets. Do not use the medicine after the expiration date printed on the package. Keep the medicine in its original container to protect it from moisture and light. Do not use damaged tablets. Do not dispose of medicines in wastewater or household waste.

