Bay Bretrax 5 mg / 1.25 mg tablets

Description: Perindopril Trihydrate 5 mg / Indapamide 1.25 mg tablets What is Perindopril Trihydrate / Indapamide and what is its use: This product consists of two active ingredients; Perindopril Trihydrate and Indapamide. Perindopril is a medicine belonging to a class of drugs known as "ACE inhibitors"; it works by dilating blood vessels, making it easier for your heart to pump blood through them. Indapamide belongs to a class of drugs known as "diuretics". Diuretics work by increasing the urine output produced by the kidneys. Indapamide differs from other diuretics because it does not cause excessive urination. This combination of active ingredients is used to help lower blood pressure and control it if you have hypertension. Do not take Perindopril Trihydrate / Indapamide: if you are allergic to Perindopril, or any other ACE inhibitor, or Indapamide, or any other sulfonamide compounds, or any other ingredients of this medication. if you have previously experienced angioedema caused by Perindopril or another ACE inhibitor. Angioedema is a condition manifested by signs and symptoms such as swelling of the face, throat, or tongue, wheezing, severe itching, or severe skin rash. if a family member has previously experienced angioedema caused by Perindopril or another ACE inhibitor. if you are pregnant for more than 3 months. if you have diabetes or kidney problems and are taking Aliskiren (a medication used to treat high blood pressure). if you have liver disease or have previously experienced hepatic encephalopathy (a brain disorder caused by severe liver damage). if you are taking Sacubitril / Valsartan (used to treat heart failure). if you are breastfeeding. if you have renal artery stenosis (narrowing of the artery supplying blood to the kidneys). if you are undergoing dialysis or any other blood filtration (depending on the type of filtration used). if you suspect untreated heart failure (the heart muscle cannot pump blood properly to the body). Precautions and warnings: Stop taking the medication immediately and talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, rash, swelling of the face or neck, low blood pressure, or dizziness. Talk to your doctor if you have hypertrophic cardiomyopathy (a heart muscle problem), or aortic stenosis (narrowing of the main blood vessel leading to the heart), or renal artery stenosis (narrowing of the artery supplying blood to the kidneys). Talk to your doctor if you suspect you have heart failure or other heart problems. Consult your doctor before starting this medication if you have liver or kidney problems or if you are on dialysis. Consult your doctor before starting this medication if you have diabetes. Consult your doctor before starting this medication if you have vasculitis (connective tissue disorder) such as scleroderma or systemic lupus erythematosus. Consult your doctor before starting this medication if you follow a salt-restricted diet or use salt substitutes containing potassium. Consult your doctor before starting this medication if you are going to undergo LDL apheresis (removal of cholesterol from your blood using a machine). Consult your doctor before starting this medication if you are going to have surgery and/or anesthesia. Consult your doctor before starting this medication if you are going to undergo desensitization therapy to reduce the effects of wasp or bee sting allergies. Consult your doctor before starting this medication if you are intolerant to certain sugars. Consult your doctor before starting this medication if you have recently experienced vomiting, diarrhea, or dehydration. Consult your doctor before starting this medication if you are pregnant or planning pregnancy. Consult your doctor before starting this medication if you have arteriosclerosis. Consult your doctor before starting this medication if you have photosensitive reactions (skin reactions when exposed to ultraviolet rays). Consult your doctor before starting this medication if you are elderly. Consult your doctor before starting this medication if you have hyperparathyroidism. Consult your doctor before starting this medication if you have gout. This medication is not recommended for hypertension in patients of African descent. It has been shown to increase the risk of angioedema and may be less effective in patients of African descent. Make sure to inform your healthcare provider that you are taking this medication if you are going to have a medical test that requires iodine contrast agent injection (used to make organs like the stomach or kidneys visible on X-rays). Make sure to inform your healthcare provider if you experience any signs of glaucoma (high eye pressure) such as vision changes or eye pain while taking this medication. If this occurs, stop taking the medication and seek immediate medical care. If you are an athlete, taking this medication may cause a positive drug test result because it contains Indapamide. Possible side effects: Rare and serious side effects include signs of allergic reactions such as; skin rash and itching, angioedema (swelling with red skin rash under the skin in a localized part of the body on the hands, feet, lips, or around the eyes), low blood pressure, bronchospasm (tightness in the chest, difficulty breathing, wheezing), irregular heartbeat, jaw, chest, and back pain due to exertion, signs of pancreatitis (fatigue and severe abdominal and back pain), signs of liver problems (yellowing of the skin or eyes, white stools, dark urine), and signs of Stevens-Johnson syndrome (a rare and severe skin disease that usually begins with flu-like symptoms followed by a painful, severe skin rash with blisters). Common side effects include dizziness, headache, vertigo, vision problems, tingling sensations, tinnitus (ringing in the ears), cough, shortness of breath, nausea, diarrhea, constipation, indigestion, taste changes, vomiting, abdominal pain, fatigue, and muscle cramps. Other medications and Perindopril Trihydrate / Indapamide: Inform your doctor or pharmacist if you are currently taking, have recently taken, or might take any other medications, including over-the-counter drugs, prescribed medications, herbal supplements, vitamins, or other supplements. If you are taking antihypertensive drugs (such as Aliskiren). If you are taking diuretics (used to increase urination). If you are taking non-steroidal anti-inflammatory drugs (used to reduce inflammation, pain, and fever such as Ibuprofen) or high-dose aspirin. If you are taking medications for diabetes (such as Metformin or Insulin). If you are taking Lithium (used for depression or mania). If you are taking Eplerenone (used for heart failure). If you are taking potassium-sparing medications (such as Spironolactone, Amiloride, Triamterene), potassium-containing salt substitutes, or potassium supplements. If you are taking Baclofen (used for muscle spasticity in conditions like multiple sclerosis). If you are taking corticosteroids or immunosuppressants (used to reduce immune response after transplantation or for autoimmune disorders such as Cyclosporine and Tacrolimus). If you are taking medications for mental health conditions such as anxiety, depression, or schizophrenia (such as antipsychotics and tricyclic antidepressants). If you are taking Heparin (blood thinner). If you are taking Procainamide (used for arrhythmias). If you are taking Estramustine (used for cancer). If you are taking Allopurinol (used for gout). If you are taking gold salts, especially when administered intravenously (used for rheumatoid arthritis). If you are taking Trimethoprim (used for infections). If you are taking vasodilators including nitrates (medications to dilate blood vessels). If you are taking medications for asthma, shock, or low blood pressure (such as Ephedrine, Epinephrine, or Norepinephrine). If you are taking Rasilez (used for hypertension). If you are taking Pentamidine (used for pneumonia). If you are taking Halofantrine (used for some types of malaria). If you are taking Sacubitril / Valsartan (used for heart failure). If you are taking Methadone (used for addiction). If you are taking Sparfloxacin or Moxifloxacin (antibiotics). If you are taking Terfenadine, Mizolastine, or Astemizole (antihistamines used for allergies or hay fever). If you are taking Vinpocetine (used for cognitive disorders with symptoms in the elderly, including memory loss). If you are taking Pebridil (used for angina). If you are taking antiarrhythmic drugs (such as Amiodarone, Quinidine, Sotalol, Hydroquinidine, Disopyramide). If you are taking Cisapride or Doxepin (for gastrointestinal issues). If you are taking Digoxin or other cardiac glycosides (used for heart problems). If you are taking calcium, including calcium supplements. If you are taking stimulant laxatives (such as Senna). If you are taking Amphotericin B by injection (used for severe fungal infections). If you are taking Tetracosactide (used for Crohn’s disease). How to take Perindopril Trihydrate / Indapamide: The recommended dose is one tablet orally once daily. Your doctor may increase the dose to two tablets daily or change the dosing schedule if you have kidney impairment. Usage instructions: Take the tablet before breakfast in the morning. Take the tablet with a full glass of water. Take the medication exactly as prescribed by your doctor. Consult your doctor or pharmacist if you are unsure. How to store Perindopril Trihydrate / Indapamide: Keep the medication out of reach of children and pets. Do not store above 30°C. Discard the blister pack after two months from first opening of the outer bag. Do not use the medication after the expiration date printed on the package. Keep the medication in its original container to protect from moisture and light. Do not use damaged tablets. Do not dispose of medications in wastewater or household waste.