Ranixa 375mg Prolonged-Release Tablets – Chronic Stable Angina Prophylaxis – 60 Tablets

Manage chronic stable angina symptoms effectively and support cardiac metabolic stability under strict clinical supervision. Ranixa 375mg is a prescription-only cardiovascular medication containing Ranolazine, formulated as prolonged-release tablets. Operating as a selective inhibitor of the late inward sodium current (I 

Na) in myocardial cells, it prevents intracellular calcium overload during ischemic events. This unique mechanism optimizes myocardial relaxation, decreases left ventricular wall tension, and lowers oxygen demand without significantly changing heart rate or systemic blood pressure, providing essential long-term maintenance therapy for stable coronary artery disease.

Key Benefits & Indications:

_ Targeted Anti-Anginal Prophylaxis: Indicated as add-on or monotherapy for the chronic management of stable angina pectoris in adults under-controlled by other anti-anginals.

_ Prolonged-Release Technology: Engineered to release the active drug gradually over hours, ensuring stable, continuous plasma concentrations and reliable round-the-clock protection.

_ Preserves Hemodynamic Balance: Reduces chest discomfort and ischemic strain efficiently without causing sudden drops in blood pressure or heart rate fluctuations.

_ Enhances Exercise Tolerance: Helps patients achieve better daily physical stamina and reduces the frequency of acute anginal attacks during exertion.

_ Myocardial Relaxation Support: Improves diastolic wall tension and coronary microcirculation by preventing harmful cellular sodium-calcium imbalances.

How to Use:

_ Physician Dosing Precision: Administer this medication exactly as directed by your treating cardiologist. The standard starting dose is typically 375mg twice daily, which may be adjusted after clinical evaluation.

_ Administration Rule: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this destroys the specialized prolonged-release coating and causes dangerous immediate drug dumping. Can be taken with or without food.

_ Dietary Restriction: Avoid consuming grapefruit juice or eating grapefruit while on this medication, as it can significantly increase Ranixa levels in the bloodstream.

Warnings & Precautions:

_ Strictly Prescription-Only: Must be used solely under the ongoing guidance, diagnostic validation, and active monitoring of a licensed physician.

_ Contraindication Advisory: Contraindicated in patients with severe renal impairment, hepatic cirrhosis, or those taking potent CYP3A4 inhibitors (like certain antifungals or clarithromycin).

_ QT Prolongation Awareness: Ranolazine can prolong the QT interval on an ECG; notify your doctor immediately if you have a personal or family history of cardiac arrhythmias or experience unexplained dizziness or syncope.

_ Storage Parameters: Store inside the original blister pack in a cool, dry area below 30°C, completely shielded from high humidity, and strictly out of reach of children.